Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.77 |
| ▸ | HDAC3 | O15379 | 14/20 | 0.77 |
| ▸ | HDAC2 | Q92769 | 14/20 | 0.77 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.77 |
| ▸ | HDAC4 | P56524 | 12/20 | 0.77 |
| ▸ | HDAC7 | Q8WUI4 | 12/20 | 0.77 |
| ▸ | HDAC10 | Q969S8 | 12/20 | 0.77 |
| ▸ | HDAC11 | Q96DB2 | 12/20 | 0.77 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.77 |
| ▸ | HDAC9 | Q9UKV0 | 12/20 | 0.77 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8204261 | 0.91 | HDAC1 (0.74) | HDAC1HDAC3HDAC2HDAC6HDAC4 | |
| SCHEMBL8209916 | 0.90 | HDAC1 (0.88) | HDAC1HDAC3HDAC2HDAC6HDAC4 | |
| SCHEMBL14147866 | 0.87 | HDAC1 (0.83) | HDAC1HDAC3HDAC2HDAC6HDAC4 | |
| SCHEMBL4342942 | 0.87 | HDAC1 (1.00) | HDAC1HDAC3HDAC2HDAC6HDAC4 | |
| SCHEMBL8209336 | 0.87 | HDAC1 (1.00) | HDAC1HDAC3HDAC2HDAC6HDAC4 | |
| SCHEMBL14066864 | 0.85 | HDAC2 (0.75) | HDAC1HDAC3HDAC2HDAC6HDAC4 | |
| SCHEMBL8201955 | 0.85 | HDAC1 (0.79) | HDAC1HDAC3HDAC2HDAC6HDAC4 | |
| SCHEMBL8209982 | 0.84 | HDAC1 (0.82) | HDAC1HDAC3HDAC2HDAC6HDAC4 | |
| SCHEMBL9344489 | 0.83 | KDM4E (0.68) | HDAC1HDAC3HDAC2HDAC6HDAC4 | |
| SCHEMBL14067956 | 0.82 | HDAC1 (0.67) | HDAC1HDAC3HDAC2HDAC6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061406-B1 | BENZAMIDO-ALKYL-HYDROXAMIC-ACID DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL COMPOSITION | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1984-06-13 | — | — | EP | claimed |
| US-4407822-A | SEDATIVES | LABORATOIRE L. LAFON (FR) | 1983-10-04 | — | — | US | disclosed |