SCHEMBL11116645

C[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	RAMP3	O60896	15/20	0.53

▸	CALCR	P30988	15/20	0.53

▸	EPHA2	P29317	3/20	0.50

▸	CXCR4	P61073	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11116638	1.00	RAMP3 (0.53)	RAMP3CALCREPHA2CXCR4
SCHEMBL29496455	0.91	RAMP3 (0.46)	RAMP3CALCREPHA2
SCHEMBL30973992	0.89	RAMP3 (0.54)	RAMP3CALCR
SCHEMBL29823809	0.87	RAMP3 (0.45)	RAMP3CALCR
SCHEMBL31416058	0.87	RAMP3 (0.52)	RAMP3CALCREPHA2
SCHEMBL31256979	0.87	MAPK8 (0.51)	RAMP3CALCREPHA2CXCR4
SCHEMBL31416061	0.87	RAMP3 (0.51)	RAMP3CALCREPHA2
SCHEMBL31694483	0.87	NMUR2 (0.53)	RAMP3CALCREPHA2CXCR4
SCHEMBL29636368	0.87	EPHA2 (0.53)	RAMP3CALCREPHA2CXCR4
SCHEMBL31126288	0.87	OPRM1 (0.42)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0108564-A1	Methods for oncogenic detection	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US)	1984-05-16	—	—	EP	disclosed