Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PDE3B | Q13370 | 7/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 3/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.43 |
| ▸ | CDK8 | P49336 | 2/20 | 0.43 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934680 | 0.90 | PDE3B (0.56) | LMNAMEN1KMT2APDE3BPDE3A | |
| SCHEMBL1392640 | 0.83 | LMNA (0.67) | LMNAMEN1KMT2APDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL7316011 | 0.82 | LMNA (0.65) | LMNAMEN1KMT2APDE3BPDE3A | |
| SCHEMBL10353678 | 0.82 | PDE3B (0.63) | LMNAMEN1KMT2APDE3BPDE3A | |
| Cadaverine Tartrate SCHEMBL8944439 | 0.78 | PDGFRB (0.49) | LMNAPDE3BPDE3AHRH3PDGFRB | |
| SCHEMBL3346610 | 0.75 | LMNA (0.60) | LMNAMEN1KMT2APDE3BPDE3A | |
| SCHEMBL3452908 | 0.74 | LMNA (0.80) | LMNAMEN1KMT2APDE3BPDE3A | |
| SCHEMBL2844945 | 0.74 | PDE3B (0.56) | PDE3BPDE3AHRH3PDGFRBCDK8 | |
| SCHEMBL8481283 | 0.74 | PDGFRB (0.59) | MEN1KMT2APDE3BPDE3ACYP1A2 | |
| SCHEMBL11474002 | 0.74 | PDE3B (0.56) | LMNAMEN1KMT2APDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116853-A1 | Pyridazinones, processes for preparing them, therapeutical compositions containing these compounds and their use | BASF Aktiengesellschaft (DE) | 1984-08-29 | — | — | EP | disclosed |