Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | PPIA | P62937 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CFD | P00746 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033584 | 0.83 | TP53 (0.75) | TP53PPIAEPHX1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5013790 | 0.82 | TP53 (1.00) | TP53PPIAEPHX1SMN1; SMN2ALDH1A1 | |
| SCHEMBL456940 | 0.81 | THRB (0.54) | TP53ALDH1A1MITFKMT2AHDAC2 | |
| SCHEMBL8000506 | 0.81 | TP53 (0.62) | TP53PPIAEPHX1SMN1; SMN2EPHX2 | |
| SCHEMBL9781823 | 0.80 | TP53 (0.66) | TP53PPIAEPHX1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8005172 | 0.79 | TP53 (0.60) | TP53PPIAEPHX1SMN1; SMN2EPHX2 | |
| SCHEMBL714625 | 0.79 | EPHX1 (0.77) | TP53PPIAEPHX1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8187605 | 0.78 | TP53 (0.58) | TP53PPIAEPHX1SMN1; SMN2ALDH1A1 | |
| SCHEMBL25658119 | 0.77 | TP53 (0.61) | TP53PPIAEPHX1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11560608 | 0.77 | TP53 (0.41) | TP53SMN1; SMN2ALDH1A1KDM4EGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052819-B1 | PROCESS FOR PREPARING AMIDINECARBOXYLIC ACIDS | UBE INDUSTRIES, LTD. (JP) | 1984-02-29 | — | — | EP | disclosed |
| US-4375554-A | REACTING AN ALKOXYIMINOACETIC ACID ESTER WITH A PRIMARY AMINE | UBE INDUSTRIES LTD. (JP) | 1983-03-01 | — | — | US | disclosed |
| EP-0052819-A1 | Process for preparing amidinecarboxylic acids | UBE INDUSTRIES, LTD. (JP) | 1982-06-02 | — | — | EP | disclosed |