Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713369 | 0.93 | MAOB (0.52) | MAOBTSHRALDH1A1MAPTGAA | |
| SCHEMBL10712815 | 0.93 | MAOB (0.48) | MAOBABCB1TSHRALDH1A1MAPT | |
| SCHEMBL10960739 | 0.89 | ALDH1A1 (0.60) | MAOBTSHRALDH1A1MAPTGAA | |
| SCHEMBL11283939 | 0.89 | ALDH1A1 (0.50) | MAOBTSHRALDH1A1MAPTGAA | |
| SCHEMBL10714188 | 0.89 | MAOB (0.50) | MAOBABCB1TSHRALDH1A1MAPT | |
| SCHEMBL10713732 | 0.89 | ALDH1A1 (0.58) | MAOBTSHRALDH1A1MAPTGAA | |
| SCHEMBL11094585 | 0.89 | MAOB (0.43) | MAOBABCB1TSHRALDH1A1MAPT | |
| SCHEMBL11085249 | 0.87 | NR1H3 (0.51) | MAOBTSHRALDH1A1MAPTGAA | |
| SCHEMBL10715640 | 0.87 | ALDH1A1 (0.50) | MAOBTSHRALDH1A1MAPTGAA | |
| SCHEMBL11085239 | 0.87 | POLB (0.49) | MAOBABCB1TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015505-B1 | 3-AMINO-1,2-PROPANE DIOLS, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USE THEREOF | CIBA-GEIGY AG (CH) | 1984-08-08 | — | — | EP | disclosed |
| EP-0015505-A1 | 3-Amino-1,2-propane diols, process for their preparation, pharmaceutical compositions containing them and use thereof | CIBA-GEIGY AG (CH) | 1980-09-17 | — | — | EP | disclosed |