Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15156605 | 1.00 | TSHR (0.57) | TSHRGPR84NAAAFFAR1MAPT | |
| SCHEMBL15157020 | 0.97 | TSHR (0.53) | TSHRGPR84NAAAFFAR1MAPT | |
| SCHEMBL15156041 | 0.95 | TSHR (0.50) | TSHRGPR84NAAAFFAR1MAPT | |
| SCHEMBL8757961 | 0.90 | TSHR (0.47) | TSHRGPR84NAAAFFAR1HCAR2 | |
| SCHEMBL17848563 | 0.83 | TSHR (0.61) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL689149 | 0.83 | TSHR (0.61) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL15066530 | 0.82 | TSHR (0.59) | TSHRNAAALCKPPARDZDHHC20 | |
| SCHEMBL27471248 | 0.82 | TSHR (0.59) | TSHRGPR84NAAAFFAR1HCAR2 | |
| SCHEMBL27480727 | 0.82 | TSHR (0.59) | TSHRGPR84NAAAFFAR1HCAR2 | |
| SCHEMBL5432582 | 0.82 | TSHR (0.59) | TSHRNAAAMAPTHCAR2RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112167-A1 | Alkali metal salts of cross-linked polymeric microgels as nucleating agents for polyethylene terephthalate moulding compositions | CELANESE CORPORATION (US) | 1984-06-27 | — | — | EP | disclosed |