Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10893501 | 0.86 | NR3C2 (0.55) | NR3C2MAPTALDH1A1TP53POLB | |
| SCHEMBL11357785 | 0.80 | KDM4E (0.47) | MAPTKDM4EALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL10784057 | 0.76 | KDM4E (0.50) | NR3C2MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10787486 | 0.76 | ALDH1A1 (0.50) | NR3C2MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10781962 | 0.75 | CYP2C9 (0.45) | MAPTKDM4EALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL10786858 | 0.75 | ALDH1A1 (0.49) | MAPTKDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL6951137 | 0.75 | MAPT (0.55) | MAPTTP53POLB | |
| SCHEMBL6951542 | 0.75 | MAPT (0.49) | MAPTKDM4EALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL10781710 | 0.73 | NR3C2 (0.53) | NR3C2MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10912750 | 0.72 | ALDH1A1 (0.48) | NR3C2MAPTKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110073-A1 | Process for the preparation of tetrahydropyridines | BAYER AG (DE) | 1984-06-13 | — | — | EP | disclosed |