Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11121605 | 0.99 | MEN1 (0.39) | MEN1KMT2ATDP1PKMRAB9A | |
| SCHEMBL11116703 | 0.87 | MEN1 (0.37) | MEN1KMT2ATDP1PKMRAB9A | |
| SCHEMBL11119842 | 0.85 | SMARCA2 (0.39) | MEN1KMT2ATDP1RPS6KA2SMARCA2 | |
| SCHEMBL11398446 | 0.81 | MEN1 (0.43) | MEN1KMT2ATDP1PKMRAB9A | |
| SCHEMBL11117030 | 0.80 | RPS6KA2 (0.36) | RAB9ARPS6KA2SMARCA2SMARCA4ALDH1A1 | |
| SCHEMBL11116634 | 0.80 | RPS6KA2 (0.36) | MEN1KMT2ARPS6KA2SMARCA2SMARCA4 | |
| SCHEMBL11119728 | 0.78 | ABCC1 (0.38) | RAB9ARPS6KA2SMARCA2SMARCA4ALDH1A1 | |
| SCHEMBL11120393 | 0.77 | MEN1 (0.40) | MEN1KMT2ATDP1PKMRAB9A | |
| SCHEMBL11116736 | 0.77 | MEN1 (0.40) | MEN1KMT2ATDP1PKMRAB9A | |
| SCHEMBL9893042 | 0.77 | GAA (0.42) | MEN1KMT2ATDP1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129408-A2 | (3-alkyl-5-isothiazolyl)ureas | ELI LILLY AND COMPANY (US) | 1984-12-27 | — | — | EP | claimed |
| EP-0129408-A2 | (3-alkyl-5-isothiazolyl)ureas | ELI LILLY AND COMPANY (US) | 1984-12-27 | — | — | EP | disclosed |