Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118931 | 0.89 | SMARCA2 (0.32) | SMARCA2SMARCA4 | |
| SCHEMBL11119728 | 0.87 | ABCC1 (0.38) | RPS6KA2SMARCA2SMARCA4HPGDTSHR | |
| SCHEMBL11119037 | 0.87 | RPS6KA2 (0.36) | RPS6KA2SMARCA2SMARCA4HPGDRAB9A | |
| SCHEMBL11119842 | 0.85 | SMARCA2 (0.39) | RPS6KA2SMARCA2SMARCA4TSHR | |
| SCHEMBL11122189 | 0.82 | NTRK1 (0.35) | RPS6KA2SMARCA2SMARCA4TSHRALDH1A1 | |
| SCHEMBL11119034 | 0.81 | NPY5R (0.41) | RPS6KA2SMARCA2SMARCA4ALDH1A1 | |
| SCHEMBL11117863 | 0.80 | MEN1 (0.40) | RPS6KA2SMARCA2SMARCA4RAB9AALDH1A1 | |
| SCHEMBL11116634 | 0.80 | RPS6KA2 (0.36) | RPS6KA2SMARCA2SMARCA4ALDH1A1 | |
| SCHEMBL9893167 | 0.79 | SMN1; SMN2 (0.43) | RPS6KA2SMARCA2SMARCA4MAPK14HPGD | |
| Hydrochloric Acid SCHEMBL11121605 | 0.79 | MEN1 (0.39) | RPS6KA2SMARCA2SMARCA4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129408-A2 | (3-alkyl-5-isothiazolyl)ureas | ELI LILLY AND COMPANY (US) | 1984-12-27 | — | — | EP | disclosed |