Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 8/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117883 | 1.00 | CYP2C9 (0.40) | CYP2C9MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11117177 | 0.99 | SPHK1 (0.40) | CYP2C9MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11117176 | 0.99 | SPHK1 (0.40) | CYP2C9MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10043256 | 0.96 | CYP2C9 (0.38) | CYP2C9MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11114552 | 0.95 | CYP2C9 (0.41) | CYP2C9MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11114554 | 0.95 | CYP2C9 (0.41) | CYP2C9MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9250291 | 0.95 | CYP2C9 (0.37) | CYP2C9MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10043258 | 0.95 | SPHK1 (0.38) | CYP2C9MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10043255 | 0.95 | CYP2C9 (0.37) | CYP2C9MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10043072 | 0.93 | CYP2C9 (0.42) | CYP2C9MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064193-B1 | 4,4'-BIS-(CYCLOHEXYL)-BIPHENYL DERIVATIVES THAT CONTAIN FLUORINE, DIELECTRICS CONTAINING THEM, AND ELECTRO-OPTICAL INDICATOR ELEMENT | MERCK PATENT GmbH (DE) | 1984-07-25 | — | — | EP | disclosed |
| US-4419264-A | Fluorine-containing 4,4'-bis-(cyclohexyl)-biphenyl derivatives, and dielectrics and electro-optical display elements containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-12-06 | — | — | US | disclosed |
| EP-0064193-A1 | 4,4'-Bis-(cyclohexyl)-biphenyl derivatives that contain fluorine, dielectrics containing them, and electro-optical indicator element | MERCK PATENT GmbH (DE) | 1982-11-10 | — | — | EP | disclosed |