SCHEMBL9250291

SCHEMBL9250291

CCCCC[C@H]1CC[C@H](c2ccc(-c3cc(F)c(F)cc3F)c(F)c2)CC1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.37
MAPT P10636 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPK1 P28482 1/20 0.36
GAA P10253 1/20 0.36
SPHK1 Q9NYA1 3/20 0.35
CYP3A4 P08684 2/20 0.34
CYP2C8 P10632 1/20 0.34
S1PR3 Q99500 1/20 0.34
ESR2 Q92731 1/20 0.33
S1PR1 P21453 5/20 0.32
SGPL1 O95470 1/20 0.32
S1PR4 O95977 1/20 0.32
S1PR5 Q9H228 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11117883 0.95 CYP2C9 (0.40) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL11117880 0.95 CYP2C9 (0.40) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL11117177 0.93 SPHK1 (0.40) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL11117176 0.93 SPHK1 (0.40) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL7916034 0.91 SPHK1 (0.37) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL7916037 0.91 SPHK1 (0.37) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL10043256 0.91 CYP2C9 (0.38) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL11114554 0.90 CYP2C9 (0.41) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL11114552 0.90 CYP2C9 (0.41) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL10043255 0.90 CYP2C9 (0.37) CYP2C9MAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995009828-A1 2,4,5-TRIFLUOROBENZENES AND THEIR USE IN LIQUID CRYSTAL MIXTURES MERCK PATENT GMBH (DE) 1995-04-13 WO disclosed