Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.58 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118382 | 0.82 | OPRM1 (0.55) | OPRM1KCNA3SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL15601041 | 0.77 | MEN1 (0.49) | OPRM1SMN1; SMN2OPRK1CYP3A4CYP2C19 | |
| SCHEMBL5682210 | 0.76 | KCNA3 (0.49) | OPRM1KCNA3SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL8561734 | 0.74 | OPRM1 (0.49) | OPRM1SMN1; SMN2OPRD1OPRK1SLC6A4 | |
| SCHEMBL5678119 | 0.73 | SMN1; SMN2 (0.50) | OPRM1KCNA3SMN1; SMN2OPRD1OPRK1 | |
| Normeperidine SCHEMBL341796 | 0.73 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SLC6A4SLC22A1 | |
| Normeperidine SCHEMBL4537496 | 0.72 | OPRM1 (0.97) | OPRM1OPRD1OPRK1SLC6A4SLC22A1 | |
| Normeperidine SCHEMBL4540908 | 0.72 | OPRM1 (0.97) | OPRM1OPRD1OPRK1SLC6A4SLC22A1 | |
| Normeperidine SCHEMBL8177568 | 0.72 | OPRM1 (0.97) | OPRM1OPRD1OPRK1SLC6A4SLC22A1 | |
| SCHEMBL21867155 | 0.72 | OPRM1 (0.48) | OPRM1SMN1; SMN2OPRD1OPRK1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121972-A2 | N-aryl-alpha-amino-carboxamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-17 | — | — | EP | disclosed |