SCHEMBL11117973

SCHEMBL11117973

c1ccc(COO[Si](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
IDO1 P14902 1/20 0.43
AGXT P21549 1/20 0.41
ALDH1A1 P00352 3/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A3 Q01959 2/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
PTGS1 P23219 1/20 0.36
CYP2C19 P33261 1/20 0.36
PTGS2 P35354 1/20 0.36
HIF1A Q16665 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.35
MAPK1 P28482 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
MAPT P10636 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10862110 0.77 TSHR (0.50) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL177923 0.75 TSHR (0.67) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL7727762 0.75 TSHR (0.35) TSHRALDH1A1CA1CA2CA9
Water SCHEMBL28419682 0.73 TSHR (0.63) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL4363419 0.73 TSHR (0.63) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL19253313 0.72 TSHR (0.44) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL1317159 0.71 TSHR (0.39) TSHRIDO1AGXTALDH1A1L3MBTL1
SCHEMBL876547 0.71 TSHR (0.60) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL1313777 0.70 TSHR (0.38) TSHRIDO1AGXTALDH1A1L3MBTL1
SCHEMBL17391615 0.68 TSHR (0.50) TSHRIDO1AGXTALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0114258-A1 Resin encapsulation type photo-semiconductor devices KABUSHIKI KAISHA TOSHIBA (JP) 1984-08-01 EP claimed