Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | RHOC | P08134 | 2/20 | 0.43 |
| ▸ | RHOA | P61586 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4089144 | 0.92 | CDK1 (0.50) | CDK1EPHX2MEN1LMNAHTT | |
| SCHEMBL19959726 | 0.90 | CDK1 (0.45) | CDK1EPHX2MEN1LMNAHTT | |
| SCHEMBL25485947 | 0.90 | CDK1 (0.45) | CDK1EPHX2MEN1LMNAHTT | |
| SCHEMBL17604064 | 0.88 | CDK1 (0.61) | CDK1EPHX2MEN1LMNAHTT | |
| SCHEMBL21400310 | 0.86 | CDK1 (0.42) | CDK1EPHX2MEN1LMNAHTT | |
| SCHEMBL29722205 | 0.85 | ALDH1A1 (0.55) | ALDH1A1 | |
| SCHEMBL19958221 | 0.85 | CDK1 (0.44) | CDK1EPHX2MEN1LMNAHTT | |
| SCHEMBL19958224 | 0.84 | CDK1 (0.43) | CDK1EPHX2MEN1LMNAHTT | |
| SCHEMBL19958226 | 0.84 | CDK1 (0.43) | CDK1EPHX2MEN1LMNAHTT | |
| SCHEMBL19958222 | 0.84 | CDK1 (0.43) | CDK1EPHX2MEN1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058868-B1 | DERIVATIVES OF TETRAHYDROPYRIMIDINON, PROCESS FOR THEIR PREPARATION AND HERBICIDES CONTAINING THOSE DERIVATIVES AS ACTIVE PRODUCTS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-04-11 | — | — | EP | disclosed |
| US-4402731-A | Herbicidally active novel substituted tetrahydropyrimidinones | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-09-06 | — | — | US | disclosed |