Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 2/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 11/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 11/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31402450 | 0.86 | TGFBR1 (0.44) | TGFBR1TAS1R3TAS1R1HDAC7HDAC8 | |
| SCHEMBL9178082 | 0.86 | TGFBR1 (0.53) | TGFBR1 | |
| SCHEMBL11054458 | 0.86 | TGFBR1 (0.46) | TGFBR1TSHR | |
| SCHEMBL274760 | 0.86 | TGFBR1 (0.61) | TGFBR1CNR1ALDH1A1TSHRADRA1A | |
| SCHEMBL28829839 | 0.85 | TGFBR1 (0.43) | TGFBR1TAS1R3TAS1R1 | |
| SCHEMBL28246144 | 0.84 | TGFBR1 (0.55) | TGFBR1CNR1HDAC6ALDH1A1ADRA1A | |
| SCHEMBL1944434 | 0.84 | TGFBR1 (0.55) | TGFBR1CNR1HDAC6ALDH1A1ADRA1A | |
| SCHEMBL2552690 | 0.79 | TGFBR1 (0.39) | TGFBR1TAS1R3TAS1R1 | |
| SCHEMBL14937691 | 0.79 | TGFBR1 (0.42) | TGFBR1TAS1R3TAS1R1 | |
| SCHEMBL20503405 | 0.79 | TGFBR1 (0.42) | TGFBR1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432884-A | COPOLYMER OF ALKYLOLAMIDE LAND ALKENYL COMPOUND | KATAYAMA CHEMICAL WORKS CO., LTD. (JP) | 1984-02-21 | — | — | US | claimed |
| US-4432884-A | COPOLYMER OF ALKYLOLAMIDE LAND ALKENYL COMPOUND | KATAYAMA CHEMICAL WORKS CO., LTD. (JP) | 1984-02-21 | — | — | US | disclosed |