Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.72 |
| ▸ | MEN1 | O00255 | 9/20 | 0.72 |
| ▸ | GAA | P10253 | 8/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11121830 | 0.84 | L3MBTL1 (0.66) | KMT2AMEN1GAAL3MBTL1MAPT | |
| SCHEMBL8206174 | 0.83 | KMT2A (1.00) | KMT2AMEN1GAAL3MBTL1MAPT | |
| SCHEMBL1421163 | 0.83 | KMT2A (1.00) | KMT2AMEN1GAAL3MBTL1MAPT | |
| SCHEMBL11118190 | 0.81 | KMT2A (0.68) | KMT2AMEN1GAAL3MBTL1MAPT | |
| SCHEMBL181796 | 0.81 | KMT2A (0.69) | KMT2AMEN1GAAL3MBTL1MAPT | |
| SCHEMBL3041005 | 0.80 | KMT2A (1.00) | KMT2AMEN1GAAL3MBTL1MAPT | |
| SCHEMBL12726822 | 0.80 | KMT2A (0.69) | KMT2AMEN1GAAL3MBTL1MAPT | |
| SCHEMBL12726838 | 0.80 | KMT2A (0.72) | KMT2AMEN1GAAL3MBTL1MAPT | |
| SCHEMBL1111137 | 0.79 | KMT2A (0.68) | KMT2AMEN1GAAL3MBTL1MAPT | |
| SCHEMBL1421509 | 0.79 | KMT2A (0.65) | KMT2AMEN1GAAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450159-A | ORGAN TRANSPLANTS; IMMUNOLOGY | THE UPJOHN COMPANY (US) | 1984-05-22 | — | — | US | claimed |