Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.66 |
| ▸ | AR | P10275 | 6/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11123437 | 1.00 | PGR (0.66) | PGRHIF1AARADORA3CYP3A4 | |
| SCHEMBL11316880 | 1.00 | PGR (0.66) | PGRHIF1AARADORA3CYP3A4 | |
| SCHEMBL11321674 | 0.96 | PGR (0.64) | PGRHIF1AARADORA3CYP3A4 | |
| SCHEMBL11120420 | 0.96 | PGR (0.64) | PGRHIF1AARADORA3CYP3A4 | |
| SCHEMBL11119948 | 0.91 | HIF1A (0.69) | PGRHIF1AARADORA3CYP3A4 | |
| SCHEMBL11327078 | 0.91 | HIF1A (0.69) | PGRHIF1AARADORA3CYP3A4 | |
| SCHEMBL11119952 | 0.91 | HIF1A (0.69) | PGRHIF1AARADORA3CYP3A4 | |
| SCHEMBL11315922 | 0.89 | PGR (0.83) | PGRHIF1AARADORA3CYP3A4 | |
| SCHEMBL11118121 | 0.89 | PGR (0.83) | PGRHIF1AARADORA3CYP3A4 | |
| SCHEMBL11120464 | 0.87 | PGR (0.60) | PGRHIF1AARADORA3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019763-B1 | CORTICOIDS, THEIR PREPARATION AND UTILIZATION | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-08-01 | — | — | EP | claimed |
| US-4289763-A | Novel corticoids, the preparation thereof and the use thereof | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-09-15 | — | — | US | claimed |
| EP-0019763-A1 | Corticoids, their preparation and utilization | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-12-10 | — | — | EP | claimed |
| EP-0019763-B1 | CORTICOIDS, THEIR PREPARATION AND UTILIZATION | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-08-01 | — | — | EP | disclosed |
| US-4289763-A | Novel corticoids, the preparation thereof and the use thereof | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-09-15 | — | — | US | disclosed |