Styrene

Styrene

SCHEMBL11118901

C=C(C)C(=O)OC.C=C(CC=CC(=O)O)C(=O)OCCCO.C=CC(=O)OCCCC.C=Cc1ccccc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
HPGD P15428 1/20 0.38
KDM4E B2RXH2 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
HCAR2 Q8TDS4 3/20 0.34
APP P05067 5/20 0.33
THRB P10828 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL9147646 0.92 TDP1 (0.40) TSHRKDM4ETDP1HCAR2APP
SCHEMBL11346702 0.91 TSHR (0.46) TSHRHPGDTDP1HCAR2ALDH1A1
Styrene SCHEMBL8982577 0.89 MEN1 (0.34) TSHRTDP1ALDH1A1MAPTPOLB
Styrene SCHEMBL6545344 0.87 TSHR (0.40) TSHRKDM4ETDP1HCAR2APP
SCHEMBL8058643 0.87 TSHR (0.46) TSHRHPGDTDP1HCAR2ALDH1A1
Styrene SCHEMBL11248244 0.86 TSHR (0.45) TSHRHPGDKDM4ETDP1HCAR2
Styrene SCHEMBL7673816 0.86 TSHR (0.39) TSHRKDM4ETDP1HCAR2APP
Styrene SCHEMBL10829930 0.86 TSHR (0.43) TSHRKDM4ETDP1HCAR2APP
SCHEMBL5007364 0.86 KDM4E (0.39) TSHRHPGDKDM4ETDP1HCAR2
SCHEMBL8144058 0.86 TDP1 (0.41) TSHRHPGDKDM4ETDP1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4215027-A Aqueous thermosettable coating compositions comprising aqueous copolymer latex, amine neutralized copolymer and melamine-formaldehyde resin CANADIAN INDUSTRIES LIMITED (CA) 1980-07-29 US claimed
US-4425450-A LOW SOLVENT CONTENT FORD MOTOR COMPANY (US) 1984-01-10 US disclosed
US-4415681-A ACRYLIC RESINS AND BUTYLATED MELAMINE-FORMALDEHYDE RESIN STABILIZER; AUTOMOBILE PAINTS FORD MOTOR COMPANY (US) 1983-11-15 US disclosed
US-4415697-A ACRYLIC THERMOSETTING RESINS; AUTOMOBILES; VARNISHES; METALLIZED COATINGS; LACQUERS FORD MOTOR COMPANY (US) 1983-11-15 US disclosed
US-4215027-A Aqueous thermosettable coating compositions comprising aqueous copolymer latex, amine neutralized copolymer and melamine-formaldehyde resin CANADIAN INDUSTRIES LIMITED (CA) 1980-07-29 US disclosed