SCHEMBL11118968

SCHEMBL11118968

Cc1c(N=C=O)c(N=C=O)c2ccccc2c1C

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.45
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
TRPA1 O75762 1/20 0.32
HSP90AA1 P07900 1/20 0.31
CYP1A2 P05177 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP1 P29466 1/20 0.31
RAB9A P51151 1/20 0.31
CASP7 P55210 1/20 0.31
ATM Q13315 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17473057 0.92 CYP3A4 (0.45) CYP3A4GABRA1GABRB2TRPA1HSP90AA1
SCHEMBL9824751 0.90 CYP3A4 (0.50) CYP3A4GABRA1GABRB2TRPA1HSP90AA1
SCHEMBL1170136 0.80 GABRA1 (0.48) CYP3A4GABRA1GABRB2TRPA1HSP90AA1
SCHEMBL1629250 0.76 CYP3A4 (0.41) CYP3A4GABRA1GABRB2TRPA1CYP1A2
SCHEMBL2814949 0.75 CYP3A4 (0.44) CYP3A4GABRA1GABRB2TRPA1TSHR
SCHEMBL2511483 0.73 CYP3A4 (0.42) CYP3A4GABRA1GABRB2TRPA1
SCHEMBL112221 0.73 CYP3A4 (0.42) CYP3A4GABRA1GABRB2TRPA1TSHR
SCHEMBL29745624 0.72 CYP3A4 (0.46) CYP3A4GABRA1GABRB2TRPA1TSHR
SCHEMBL57779 0.72 CYP3A4 (0.46) CYP3A4GABRA1GABRB2TRPA1TSHR
SCHEMBL664224 0.72 CYP3A4 (0.46) CYP3A4GABRA1GABRB2TRPA1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118302407-A Carbonyl compound, method for producing isocyanate compound, and isocyanate composition 旭化成株式会社 2024-07-05 CN disclosed
CN-118215651-A Method for producing isocyanate compound, method for producing urethane compound, method for recovering amine compound, and isocyanate composition 旭化成株式会社 2024-06-18 CN disclosed
EP-0035072-B1 DUROPLASTICALLY HARDENABLE RESIN MIXTURE FREE OF SOLVENTS, AND ITS USE BBC Aktiengesellschaft Brown, Boveri & Cie. (CH) 1984-06-13 EP disclosed
US-4384101-A EPOXIDE, ISOCYANATE, TRIALLYL CYANURATE AS CROSSLINKER FOR THERMOSETTING ELECTRICAL INSULATION BBC BROWN, BOVERI & COMPANY, LIMITED (CH) 1983-05-17 US disclosed
WO-1981002647-A1 RESINOUS MIXTURE BBC BROWN BOVERI & CIE (CH) 1981-09-17 WO disclosed
EP-0035072-A1 Duroplastically hardenable resin mixture free of solvents, and its use BBC Aktiengesellschaft Brown, Boveri & Cie. (CH) 1981-09-09 EP disclosed