Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10999589 | 0.84 | MEN1 (0.49) | CYP19A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL20963179 | 0.81 | CYP19A1 (0.49) | CYP19A1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL10972636 | 0.80 | NPSR1 (0.48) | CYP19A1MEN1KMT2AALDH1A1HSP90AA1 | |
| SCHEMBL10970720 | 0.80 | CYP19A1 (0.53) | CYP19A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL11089745 | 0.80 | CYP19A1 (0.43) | CYP19A1MEN1KMT2AALDH1A1 | |
| SCHEMBL10947079 | 0.78 | MAPT (0.49) | CYP19A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL27517941 | 0.78 | CYP19A1 (0.46) | CYP19A1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL10959984 | 0.78 | CYP19A1 (0.56) | CYP19A1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7674570 | 0.75 | CYP19A1 (0.79) | CYP19A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL12462114 | 0.75 | CYP19A1 (0.53) | CYP19A1MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127865-A1 | Novel triazolyl-substituted propane derivatives, their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1984-12-12 | — | — | EP | disclosed |