Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711370 | 0.91 | CYP19A1 (0.47) | CYP19A1HTTKDM4EPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL10832295 | 0.85 | ALDH1A1 (0.47) | CYP19A1HTTKDM4EPOLBKMT2A | |
| SCHEMBL11375336 | 0.85 | CYP19A1 (0.51) | CYP19A1HTTKDM4EPOLBKMT2A | |
| Ammonia Solution, Strong SCHEMBL9422751 | 0.84 | CYP19A1 (0.42) | CYP19A1HTTKDM4EPOLBKMT2A | |
| SCHEMBL9634892 | 0.83 | CYP19A1 (0.50) | CYP19A1HTTKDM4EPOLBKMT2A | |
| SCHEMBL9657263 | 0.83 | CYP19A1 (0.50) | CYP19A1HTTKDM4EPOLBKMT2A | |
| SCHEMBL12532514 | 0.83 | CYP19A1 (0.50) | CYP19A1HTTKDM4EPOLBKMT2A | |
| SCHEMBL10971308 | 0.83 | CYP19A1 (0.40) | CYP19A1HTTKDM4EPOLBKMT2A | |
| SCHEMBL10972636 | 0.83 | NPSR1 (0.48) | CYP19A1KMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL11089745 | 0.83 | CYP19A1 (0.43) | CYP19A1POLBKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148858-A1 | NOVEL TRIAZOLYL-SUBSTITUTED PROPANE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1985-07-24 | — | — | EP | claimed |
| WO-1984004918-A1 | NOVEL TRIAZOLYL-SUBSTITUTED PROPANE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORP (US) | 1984-12-20 | — | — | WO | claimed |
| EP-0127865-A1 | Novel triazolyl-substituted propane derivatives, their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1984-12-12 | — | — | EP | claimed |
| US-4482564-A | FUNGICIDES | SCHERING CORPORATION (US) | 1984-11-13 | — | — | US | claimed |
| EP-0148858-A1 | NOVEL TRIAZOLYL-SUBSTITUTED PROPANE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1985-07-24 | — | — | EP | disclosed |
| WO-1984004918-A1 | NOVEL TRIAZOLYL-SUBSTITUTED PROPANE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORP (US) | 1984-12-20 | — | — | WO | disclosed |
| EP-0127865-A1 | Novel triazolyl-substituted propane derivatives, their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1984-12-12 | — | — | EP | disclosed |
| US-4482564-A | FUNGICIDES | SCHERING CORPORATION (US) | 1984-11-13 | — | — | US | disclosed |