Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAG | P20916 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9473154 | 0.93 | L3MBTL1 (0.53) | L3MBTL1MAGPOLBMAPK1LMNA | |
| SCHEMBL10947656 | 0.86 | L3MBTL1 (0.52) | L3MBTL1MAGPOLBMAPK1LMNA | |
| SCHEMBL11281689 | 0.84 | L3MBTL1 (0.50) | L3MBTL1MAGPOLBKMT2AHCRTR2 | |
| SCHEMBL6833949 | 0.82 | L3MBTL1 (0.77) | L3MBTL1MAGPOLBMAPK1LMNA | |
| SCHEMBL15513804 | 0.82 | L3MBTL1 (0.77) | L3MBTL1MAGPOLBMAPK1LMNA | |
| SCHEMBL11565600 | 0.82 | L3MBTL1 (0.77) | L3MBTL1MAGPOLBMAPK1LMNA | |
| SCHEMBL8571903 | 0.82 | L3MBTL1 (0.77) | L3MBTL1MAGPOLBMAPK1LMNA | |
| SCHEMBL10542172 | 0.82 | L3MBTL1 (0.77) | L3MBTL1MAGPOLBMAPK1LMNA | |
| SCHEMBL8332499 | 0.82 | L3MBTL1 (0.77) | L3MBTL1MAGPOLBMAPK1LMNA | |
| SCHEMBL10545105 | 0.82 | L3MBTL1 (0.77) | L3MBTL1MAGPOLBMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0039637-B1 | IMMUNOLOGICALLY ACTIVE DIPEPTIDYL 5-0,6-0-ACYL-2-AMINO-2-DEOXY-D-GLUCOFURANOSE DERIVATIVES AND METHODS OF PREPARATION | MERCK & CO. INC. (US) | 1984-03-28 | — | — | EP | disclosed |
| US-4310514-A | VACCINES | MERCK & CO., INC. (US) | 1982-01-12 | — | — | US | disclosed |
| EP-0039637-A1 | Immunologically active dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-D-glucofuranose derivatives and methods of preparation | MERCK & CO. INC. (US) | 1981-11-11 | — | — | EP | disclosed |