Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 4/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126617 | 0.76 | PTGIR (0.44) | PTGIRFABP4FABP5MEN1KMT2A | |
| SCHEMBL11258884 | 0.76 | FABP4 (0.54) | PTGIRFABP4FABP5MEN1GLA | |
| SCHEMBL11255916 | 0.76 | FABP4 (0.54) | PTGIRFABP4FABP5MEN1GLA | |
| SCHEMBL11267074 | 0.76 | FABP4 (0.54) | PTGIRFABP4FABP5MEN1GLA | |
| SCHEMBL11255610 | 0.76 | FABP4 (0.54) | PTGIRFABP4FABP5MEN1GLA | |
| SCHEMBL8114438 | 0.76 | PTGIR (0.54) | PTGIRFABP4FABP5TBXAS1PTGS1 | |
| SCHEMBL11123285 | 0.76 | PTGIR (0.54) | PTGIRFABP4FABP5TBXAS1PTGS1 | |
| SCHEMBL11125777 | 0.75 | FABP4 (0.52) | PTGIRFABP4FABP5MEN1GLA | |
| SCHEMBL11125751 | 0.75 | PTGIR (0.53) | PTGIRFABP4FABP5TBXAS1 | |
| SCHEMBL11120957 | 0.75 | PTGIR (0.53) | PTGIRFABP4FABP5TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051829-B1 | N-SUBSTITUTED OMEGA-(2-OXO-4-IMIDAZOLIN-1-YL) ALCANOIC ACIDS, SALTS AND ESTERS THEREOF, PROCESS FOR PRODUCING THE SAME AND THESE ACTIVE AGENTS CONTAINING PHARMACEUTICAL COMPOUNDS | A. Nattermann & Cie. GmbH (DE) | 1984-12-05 | — | — | EP | claimed |
| US-4349684-A | ANTIALLERGENS, ANTIASTHMATICS | A. NATTERMANN & CIE GMBH (DE) | 1982-09-14 | — | — | US | claimed |
| EP-0051829-A1 | N-substituted omega-(2-oxo-4-imidazolin-1-yl) alcanoic acids, salts and esters thereof, process for producing the same and these active agents containing pharmaceutical compounds | A. Nattermann & Cie. GmbH (DE) | 1982-05-19 | — | — | EP | claimed |
| EP-0051829-B1 | N-SUBSTITUTED OMEGA-(2-OXO-4-IMIDAZOLIN-1-YL) ALCANOIC ACIDS, SALTS AND ESTERS THEREOF, PROCESS FOR PRODUCING THE SAME AND THESE ACTIVE AGENTS CONTAINING PHARMACEUTICAL COMPOUNDS | A. Nattermann & Cie. GmbH (DE) | 1984-12-05 | — | — | EP | disclosed |
| US-4349684-A | ANTIALLERGENS, ANTIASTHMATICS | A. NATTERMANN & CIE GMBH (DE) | 1982-09-14 | — | — | US | disclosed |
| EP-0051829-A1 | N-substituted omega-(2-oxo-4-imidazolin-1-yl) alcanoic acids, salts and esters thereof, process for producing the same and these active agents containing pharmaceutical compounds | A. Nattermann & Cie. GmbH (DE) | 1982-05-19 | — | — | EP | disclosed |