Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422948 | 0.89 | HSD17B10 (0.58) | HSD17B10MEN1POLBKMT2ATDP1 | |
| SCHEMBL17244862 | 0.84 | HSD17B10 (0.54) | HSD17B10TDP1SPHK1MAPK1 | |
| SCHEMBL8578960 | 0.82 | MEN1 (0.48) | HSD17B10MEN1POLBKMT2AKDM4E | |
| SCHEMBL10394501 | 0.81 | HSD17B10 (0.54) | HSD17B10TDP1KDM4ELMNASPHK1 | |
| SCHEMBL5709862 | 0.81 | HSD17B10 (0.50) | HSD17B10TDP1SPHK1ALDH1A1MAPK1 | |
| SCHEMBL27847722 | 0.79 | HSD17B10 (0.59) | HSD17B10TDP1KDM4ELMNACYP1A2 | |
| SCHEMBL22184548 | 0.77 | HSD17B10 (0.56) | HSD17B10TDP1KDM4ELMNACYP1A2 | |
| SCHEMBL4537695 | 0.77 | HSD17B10 (0.56) | HSD17B10TDP1KDM4ELMNACYP1A2 | |
| SCHEMBL5709865 | 0.76 | HSD17B10 (0.54) | HSD17B10TDP1SPHK1MAPK1 | |
| SCHEMBL6555797 | 0.75 | HSD17B10 (0.74) | HSD17B10MEN1KMT2ATDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4380591-A | POLYESTER URETHANE COPOLYMER | UNION CARBIDE CORPORATION (US) | 1983-04-19 | — | — | US | disclosed |
| US-4379757-A | Tertiary amine catalyst mixtures useful in cellular polyurethane formation | UNION CARBIDE CORPORATION (US) | 1983-04-12 | — | — | US | disclosed |
| EP-0048985-A1 | Process for cellular polyurethane formation using tertiary amine catalyst mixtures | UNION CARBIDE CORPORATION (US) | 1982-04-07 | — | — | EP | disclosed |