Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709862 | 0.91 | HSD17B10 (0.50) | HSD17B10TDP1MAPK1SPHK1 | |
| SCHEMBL17244862 | 0.91 | HSD17B10 (0.54) | HSD17B10TDP1MAPK1SPHK1BLM | |
| SCHEMBL11124129 | 0.89 | HSD17B10 (0.58) | HSD17B10TDP1MAPK1SPHK1MEN1 | |
| SCHEMBL4537695 | 0.83 | HSD17B10 (0.56) | HSD17B10TDP1MAPK1SPHK1PMP22 | |
| SCHEMBL22184548 | 0.83 | HSD17B10 (0.56) | HSD17B10TDP1MAPK1SPHK1PMP22 | |
| SCHEMBL5709865 | 0.81 | HSD17B10 (0.54) | HSD17B10TDP1MAPK1SPHK1FYN | |
| SCHEMBL6555797 | 0.81 | HSD17B10 (0.74) | HSD17B10TDP1MAPK1SPHK1FYN | |
| SCHEMBL2065402 | 0.79 | HSD17B10 (0.33) | HSD17B10BLMPMP22MEN1POLB | |
| SCHEMBL170070 | 0.78 | HSD17B10 (0.70) | HSD17B10TDP1MAPK1SPHK1FYN | |
| SCHEMBL11739597 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948502-A1 | CYANOPHOSPHORUS COMPOUNDS AND THEIR PREPARATION | MONSANTO COMPANY (US) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998029419-A1 | CYANOPHOSPHORUS COMPOUNDS AND THEIR PREPARATION | MONSANTO COMPANY (US) | 1998-07-09 | — | — | WO | disclosed |
| EP-0755185-A1 | MICROBICIDAL AGENTS BASED ON DIBROMO-THIOPHENE-CARBOXYLIC ACID DERIVATIVES | BAYER AG (DE) | 1997-01-29 | — | — | EP | disclosed |
| EP-0707578-A1 | 2-OXIMINO-2-THIENYL-ACETIC ACID DERIVATIVES | BAYER AG (DE) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995027397-A1 | MICROBICIDAL AGENTS BASED ON DIBROMO-THIOPHENE-CARBOXYLIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-19 | — | — | WO | disclosed |