Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.97 |
| ▸ | NPC1 | O15118 | 6/20 | 0.97 |
| ▸ | GAA | P10253 | 6/20 | 0.97 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14832820 | 1.00 | RAB9A (0.97) | RAB9ANPC1GAAMAPTALDH1A1 | |
| SCHEMBL15216572 | 0.93 | RAB9A (0.84) | RAB9ANPC1GAAMAPTALDH1A1 | |
| SCHEMBL14831808 | 0.82 | RAB9A (0.69) | RAB9ANPC1GAAMAPTALDH1A1 | |
| SCHEMBL11127223 | 0.82 | RAB9A (0.69) | RAB9ANPC1GAAMAPTALDH1A1 | |
| SCHEMBL5778611 | 0.82 | RAB9A (0.68) | RAB9ANPC1GAAMAPTALDH1A1 | |
| SCHEMBL14438165 | 0.81 | NOX1 (0.74) | RAB9ANPC1GAAMAPTALDH1A1 | |
| SCHEMBL11127219 | 0.81 | NOX1 (0.74) | RAB9ANPC1GAAMAPTALDH1A1 | |
| SCHEMBL11674398 | 0.81 | NOX1 (0.74) | RAB9ANPC1GAAMAPTALDH1A1 | |
| SCHEMBL11674396 | 0.81 | NOX1 (0.74) | RAB9ANPC1GAAMAPTALDH1A1 | |
| SCHEMBL14832809 | 0.81 | RAB9A (0.67) | RAB9ANPC1GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013046041-A1 | PYRIDINYLPYRAZOLES FOR USE AS KINASE MODULATORS FOR THE TREATMENT OF CANCER | SYNOVO GMBH (DE) | 2013-04-04 | — | — | WO | disclosed |
| EP-0023652-B1 | PROCESS FOR THE PREPARATION OF CATIONIC DYESTUFFS | BAYER AG (DE) | 1984-05-09 | — | — | EP | disclosed |
| EP-0023652-A1 | Process for the preparation of cationic dyestuffs | BAYER AG (DE) | 1981-02-11 | — | — | EP | disclosed |