Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 4/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | GPX4 | P36969 | 1/20 | 0.34 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11121027 | 0.87 | TP53 (0.74) | TP53ALDH1A1TDP1NR1I2CYP3A4 | |
| SCHEMBL9292388 | 0.85 | TP53 (0.48) | TP53ALDH1A1TDP1NR1I2CYP3A4 | |
| SCHEMBL9614029 | 0.84 | TP53 (0.71) | TP53ALDH1A1TDP1NR1I2CYP3A4 | |
| SCHEMBL10858355 | 0.79 | TP53 (0.74) | TP53ALDH1A1TDP1NR1I2CYP3A4 | |
| SCHEMBL11762160 | 0.75 | TP53 (0.50) | TP53ALDH1A1TDP1NR1I2CYP3A4 | |
| SCHEMBL11097795 | 0.75 | TP53 (0.53) | TP53ALDH1A1TDP1NR1I2CYP3A4 | |
| SCHEMBL9614019 | 0.75 | TP53 (0.56) | TP53ALDH1A1TDP1NR1I2CYP3A4 | |
| SCHEMBL9292414 | 0.74 | TP53 (0.44) | TP53ALDH1A1TDP1NR1I2CYP3A4 | |
| SCHEMBL11101707 | 0.74 | TP53 (0.55) | TP53ALDH1A1TDP1NR1I2CYP3A4 | |
| SCHEMBL11875296 | 0.74 | TP53 (0.57) | TP53ALDH1A1TDP1NR1I2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057588-B1 | PROCESS FOR PRODUCING N-(HALOMETHYL)ACYLAMIDES | MONSANTO COMPANY (US) | 1984-03-21 | — | — | EP | disclosed |
| EP-0057588-A2 | Process for producing N-(halomethyl)acylamides | MONSANTO COMPANY (US) | 1982-08-11 | — | — | EP | disclosed |
| US-4322553-A | BY REACTING THE CORRESPONDING N-/ALKOXYMETHYL/ACRYLAMIDE WITH THTONYL CHLORIDE OR THIONYL BROMIDE | MONSANTO COMPANY (US) | 1982-03-30 | — | — | US | disclosed |