SCHEMBL9614029

SCHEMBL9614029

CCc1cccc(CC)c1N(CCl)C(=O)CCl

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 6/20 0.71
NR1I2 O75469 1/20 0.64
TDP1 Q9NUW8 2/20 0.62
KMT2A Q03164 2/20 0.62
MEN1 O00255 1/20 0.62
ALDH1A1 P00352 9/20 0.60
CYP3A4 P08684 1/20 0.60
RAB9A P51151 6/20 0.43
NPC1 O15118 5/20 0.43
PAX8 Q06710 4/20 0.43
JAK2 O60674 2/20 0.43
GPX4 P36969 1/20 0.41
HTT P42858 5/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
GLA P06280 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
LMNA P02545 2/20 0.40
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10858355 0.90 TP53 (0.74) TP53NR1I2TDP1KMT2AMEN1
SCHEMBL11875296 0.88 TP53 (0.57) TP53NR1I2TDP1KMT2AMEN1
SCHEMBL27976189 0.88 TP53 (0.69) TP53NR1I2TDP1KMT2AMEN1
SCHEMBL11102927 0.86 TP53 (0.68) TP53NR1I2TDP1KMT2AMEN1
SCHEMBL9614019 0.86 TP53 (0.56) TP53NR1I2TDP1KMT2AMEN1
SCHEMBL11101707 0.85 TP53 (0.55) TP53NR1I2TDP1KMT2AMEN1
SCHEMBL3695063 0.85 TP53 (0.66) TP53NR1I2TDP1KMT2AMEN1
SCHEMBL131683 0.85 TP53 (0.66) TP53NR1I2TDP1KMT2AMEN1
SCHEMBL11125347 0.84 TP53 (0.53) TP53NR1I2TDP1KMT2AMEN1
SCHEMBL9420240 0.83 TP53 (0.84) TP53NR1I2TDP1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109019811-B Organic iron-based flocculating agent for treating papermaking wastewater and preparation method thereof 山东博汇纸业股份有限公司 2021-10-01 CN claimed
US-5155272-A Process for the production of haloacylamides MONSANTO COMPANY (US) 1992-10-13 US claimed
EP-0053495-B1 PROCESS FOR PRODUCING N-(HALOMETHYL) ACYLAMIDES MONSANTO COMPANY (US) 1984-08-08 EP claimed
EP-0057588-B1 PROCESS FOR PRODUCING N-(HALOMETHYL)ACYLAMIDES MONSANTO COMPANY (US) 1984-03-21 EP claimed
EP-0057588-A2 Process for producing N-(halomethyl)acylamides MONSANTO COMPANY (US) 1982-08-11 EP claimed
EP-0053495-A1 Process for producing N-(halomethyl) acylamides MONSANTO COMPANY (US) 1982-06-09 EP claimed
US-4322553-A BY REACTING THE CORRESPONDING N-/ALKOXYMETHYL/ACRYLAMIDE WITH THTONYL CHLORIDE OR THIONYL BROMIDE MONSANTO COMPANY (US) 1982-03-30 US claimed
US-4311858-A Process for producing N-(halomethyl) acyl-amides MONSANTO COMPANY (US) 1982-01-19 US claimed
JP-58103351-A None JP disclosed
CN-116178199-A Preparation method of N-chloroacetanilide herbicide 辽阳恒业化工有限公司 2023-05-30 CN disclosed
CN-109019811-B Organic iron-based flocculating agent for treating papermaking wastewater and preparation method thereof 山东博汇纸业股份有限公司 2021-10-01 CN disclosed
CN-109019811-A A kind of pulping wastewater treatment flocculant and preparation method thereof based on Organic Iron 师帅帅 2018-12-18 CN disclosed
US-5155272-A Process for the production of haloacylamides MONSANTO COMPANY (US) 1992-10-13 US disclosed
US-4798618-A Novel chloroacetanilide derivatives and herbicides containing the same for use in paddy field AGRO-KANESHO CO., LTD. (JP) 1989-01-17 US disclosed
EP-0057588-A2 Process for producing N-(halomethyl)acylamides MONSANTO COMPANY (US) 1982-08-11 EP disclosed
EP-0053495-A1 Process for producing N-(halomethyl) acylamides MONSANTO COMPANY (US) 1982-06-09 EP disclosed
US-4322553-A BY REACTING THE CORRESPONDING N-/ALKOXYMETHYL/ACRYLAMIDE WITH THTONYL CHLORIDE OR THIONYL BROMIDE MONSANTO COMPANY (US) 1982-03-30 US disclosed
US-4319917-A N-(2-Cyanoalkoxy)methyl-N-(2-,3-, or 6-alkylphenyl)-α-haloacetamides PPG INDUSTRIES, INC. (US) 1982-03-16 US disclosed
US-4311858-A Process for producing N-(halomethyl) acyl-amides MONSANTO COMPANY (US) 1982-01-19 US disclosed
US-3976471-A HERBICIDE VELSICOL CHEMICAL CORPORATION (US) 1976-08-24 US disclosed