Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9639948 | 0.84 | NPSR1 (0.58) | NPSR1ALDH1A1HSD17B10LMNAHCAR2 | |
| SCHEMBL221523 | 0.84 | NPSR1 (0.58) | NPSR1ALDH1A1HSD17B10LMNAHCAR2 | |
| SCHEMBL136952 | 0.84 | NPSR1 (0.58) | NPSR1ALDH1A1HSD17B10LMNAHCAR2 | |
| SCHEMBL3289401 | 0.80 | NPSR1 (0.54) | NPSR1ALDH1A1HSD17B10LMNAHCAR2 | |
| SCHEMBL3289399 | 0.80 | NPSR1 (0.54) | NPSR1ALDH1A1HSD17B10LMNAHCAR2 | |
| SCHEMBL9640847 | 0.80 | NPSR1 (0.54) | NPSR1ALDH1A1HSD17B10LMNAHCAR2 | |
| SCHEMBL11130729 | 0.78 | MAPT (0.41) | NPSR1ALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL11130732 | 0.78 | MAPT (0.41) | NPSR1ALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL2952591 | 0.77 | NPSR1 (0.56) | NPSR1ALDH1A1HSD17B10LMNAHCAR2 | |
| SCHEMBL9512735 | 0.77 | NPSR1 (0.56) | NPSR1ALDH1A1HSD17B10LMNAHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043088-B1 | PROCESS FOR THE PRODUCTION OF ALKYL ESTERS OF ACETOACTIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-01-18 | — | — | EP | disclosed |