Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640847 | 1.00 | NPSR1 (0.54) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL3289401 | 1.00 | NPSR1 (0.54) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL9639948 | 0.86 | NPSR1 (0.58) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL136952 | 0.86 | NPSR1 (0.58) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL221523 | 0.86 | NPSR1 (0.58) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL10532252 | 0.82 | ALDH1A1 (0.44) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL11126166 | 0.80 | NPSR1 (0.52) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL19397674 | 0.79 | ATM (0.59) | NPSR1HCAR2ALDH1A1MAPTRAB9A | |
| SCHEMBL28006779 | 0.79 | ATM (0.59) | NPSR1HCAR2ALDH1A1MAPTRAB9A | |
| SCHEMBL23142290 | 0.78 | NPSR1 (0.45) | NPSR1ALDH1A1LMNAHSD17B10MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230107216-A1 | PANTETHEINE DERIVATIVES AND USES THEREOF | VECTIVBIO COMET AG, F/K/A COMET THERAPEUTICS, INC. (CH) | 2023-04-06 | — | — | US | disclosed |
| US-20200255395-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | KUALITY HERBCEUTICS LLC (US) | 2020-08-13 | — | — | US | disclosed |
| US-10584108-B2 | Therapeutic compounds and methods of use thereof | KUALITY HERBCEUTICS LLC (US) | 2020-03-10 | — | — | US | disclosed |
| EP-2781519-B1 | NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVE AND A PRODUCTION METHOD FOR SAME | ST PHARM CO LTD (KR) | 2019-10-30 | — | — | EP | disclosed |
| US-20180134679-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | KUALITY HERBCEUTICS LLC (US) | 2018-05-17 | — | — | US | disclosed |
| US-9758690-B2 | Transparent resin composition for sealing organic electroluminescence element, resin sheet for sealing organic electroluminescence element, and apparatus for displaying image | FURUKAWA ELECTRIC CO., LTD. (JP) | 2017-09-12 | — | — | US | disclosed |
| US-9499537-B2 | Antiviral pyrrolopyridine derivatives and method for preparing the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2016-11-22 | — | — | US | disclosed |
| WO-2016179587-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | KUALITY HERBCEUTICS LLC (US) | 2016-11-10 | — | — | WO | disclosed |
| US-20150291824-A1 | TRANSPARENT RESIN COMPOSITION FOR SEALING ORGANIC ELECTROLUMINESCENCE ELEMENT, RESIN SHEET FOR SEALING ORGANIC ELECTROLUMINESCENCE ELEMENT, AND APPARATUS FOR DISPLAYING IMAGE | FURUKAWA ELECTRIC CO., LTD. (JP) | 2015-10-15 | — | — | US | disclosed |
| EP-2781519-A1 | NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVE AND A PRODUCTION METHOD FOR SAME | Korea Research Institute of Chemical Technology (KR) | 2014-09-24 | — | — | EP | disclosed |
| US-20140249162-A1 | NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVES AND METHOD FOR PREPARING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2014-09-04 | — | — | US | disclosed |
| US-7723065-B2 | Conditions for reactions mediated by yeast | VICTORIA UNIVERSITY (AU) | 2010-05-25 | — | — | US | disclosed |
| US-20070212819-A1 | Silicone Adhesive | MOMENTIVE PERFORMANCE MATERIALS JAPAN LLC (JP) | 2007-09-13 | — | — | US | disclosed |
| US-20050084943-A1 | New conditions for reactions mediated by yeast | VICTORIA UNIVERSITY OF TECHNOLOGY (AU) | 2005-04-21 | — | — | US | disclosed |
| US-20030181515-A1 | Methods of using kavalactone compositions | KAVA PHARMACEUTICALS, INC., A DELAWARE CORPORATION | 2003-09-25 | — | — | US | disclosed |
| US-20020192241-A1 | Methods of using kavalactone compositions | SYNTA PHARMACEUTICALS CORP. | 2002-12-19 | — | — | US | disclosed |
| US-20020187169-A1 | Kavalactone compositions | SYNTA PHARMACEUTICALS CORP. | 2002-12-12 | — | — | US | disclosed |
| US-4855320-A | ANTICONVULSANTS, ANTIEPILEPTICS | DR. WILLMAR SCHWABE GMBH & COMPANY (DE) | 1989-08-08 | — | — | US | disclosed |
| US-4766213-A | 1,4-dihydropyridines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-08-23 | — | — | US | disclosed |
| US-4431668-A | INSECTICIDES; PESTICIDES; PHOTOSTABILITY | DAINIPPON JOCHUGIKU KABUSHIKI KAISHA (JP) | 1984-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230107216-A1 | PANTETHEINE DERIVATIVES AND USES THEREOF | VNN1, NQO1, VKORC1 | NPSR1 2430/4885HCAR2 1720/4885ALDH1A1 806/4885 |
| US-20180134679-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | NQO1, VHL, XIAP | NPSR1 1750/4885HCAR2 833/4885ALDH1A1 223/4885 |
| US-20200255395-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | NQO1, VHL, XIAP | NPSR1 1750/4885HCAR2 833/4885ALDH1A1 223/4885 |
| US-20140249162-A1 | NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVES AND METHOD FOR PREPARING THE SAME | MAVS, IMPDH1, SARS1 | NPSR1 3218/4885HCAR2 3779/4885ALDH1A1 2320/4885 |
| US-20020187169-A1 | Kavalactone compositions | KLK14, KLHL20, KLHL6 | NPSR1 4537/4885HCAR2 3446/4885ALDH1A1 2448/4885 |
| US-10584108-B2 | Therapeutic compounds and methods of use thereof | NQO1, VHL, XIAP | NPSR1 1750/4885HCAR2 833/4885ALDH1A1 223/4885 |
| US-20030181515-A1 | Methods of using kavalactone compositions | KHK, KLK4, KLK14 | NPSR1 4379/4885HCAR2 3286/4885ALDH1A1 2705/4885 |
| US-20020192241-A1 | Methods of using kavalactone compositions | KHK, KLK4, KLK14 | NPSR1 4379/4885HCAR2 3286/4885ALDH1A1 2705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.