Hydantoin

Hydantoin

SCHEMBL11127367

C=C(C)C.O=C1CNC(=O)N1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.41
MB P02144 2/20 0.34
PDE3B Q13370 1/20 0.31
PDE3A Q14432 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydantoin SCHEMBL10636755 0.88 CRBN (0.42) CRBNMBPDE3BPDE3A
Hydantoin SCHEMBL30023441 0.87 CRBN (0.35) CRBNMB
Hydantoin SCHEMBL2875362 0.86 CRBN (0.41) CRBNMBPDE3BPDE3A
Hydantoin SCHEMBL10324706 0.86 TDP1 (0.46) CRBNMB
Hydantoin SCHEMBL7071652 0.85
Hydantoin SCHEMBL9798274 0.85
Hydantoin SCHEMBL28169152 0.85
Hydantoin SCHEMBL8439389 0.85 CRBN (0.48) CRBNMBPDE3BPDE3A
Hydantoin SCHEMBL27690 0.84
Hydantoin SCHEMBL7285865 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116803988-A Synthesis method of isobutylidene hydantoin 浙江昂利泰制药有限公司 2023-09-26 CN disclosed
US-4434071-A 1,3-Dibromo dialkylhydantoin and olefin oligomer reaction product as a catalyst for preparing alkenyl dicarboxylic acid anhydride TEXACO INC. (US) 1984-02-28 US disclosed