Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PTGIR | P43119 | 2/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11124380 | 0.89 | FAAH (0.60) | FAAHTP53LMNALTB4RKDM4E | |
| SCHEMBL11120957 | 0.87 | PTGIR (0.53) | FAAHPTGIR | |
| SCHEMBL11125751 | 0.87 | PTGIR (0.53) | FAAHPTGIR | |
| SCHEMBL11127880 | 0.85 | FAAH (0.56) | FAAHTP53LMNALTB4RKDM4E | |
| SCHEMBL11514227 | 0.80 | KDM4E (0.54) | FAAHTP53KDM4EMEN1ALDH1A1 | |
| SCHEMBL11516177 | 0.80 | KDM4E (0.54) | FAAHTP53KDM4EMEN1ALDH1A1 | |
| SCHEMBL8104091 | 0.79 | FAAH (0.62) | FAAHKDM4EALDH1A1GAATNF | |
| SCHEMBL11134620 | 0.78 | CNR2 (0.53) | FAAHKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL5720289 | 0.76 | FAAH (0.59) | FAAHGAATNF | |
| SCHEMBL8113970 | 0.76 | FAAH (0.76) | FAAHTP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051829-B1 | N-SUBSTITUTED OMEGA-(2-OXO-4-IMIDAZOLIN-1-YL) ALCANOIC ACIDS, SALTS AND ESTERS THEREOF, PROCESS FOR PRODUCING THE SAME AND THESE ACTIVE AGENTS CONTAINING PHARMACEUTICAL COMPOUNDS | A. Nattermann & Cie. GmbH (DE) | 1984-12-05 | — | — | EP | disclosed |
| US-4349684-A | ANTIALLERGENS, ANTIASTHMATICS | A. NATTERMANN & CIE GMBH (DE) | 1982-09-14 | — | — | US | disclosed |
| EP-0051829-A1 | N-substituted omega-(2-oxo-4-imidazolin-1-yl) alcanoic acids, salts and esters thereof, process for producing the same and these active agents containing pharmaceutical compounds | A. Nattermann & Cie. GmbH (DE) | 1982-05-19 | — | — | EP | disclosed |