SCHEMBL11128583

SCHEMBL11128583

CCOP(=O)(Oc1ccccc1)c1cccs1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA4 P22748 1/20 0.47
CA5A P35218 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA5B Q9Y2D0 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
NPSR1 Q6W5P4 1/20 0.39
MMP9 P14780 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
MMP1 P03956 1/20 0.38
MMP3 P08254 1/20 0.38
ADAM17 P78536 1/20 0.38
ADAM9 Q13443 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11124058 0.85 L3MBTL1 (0.53) CA12CA1CA2CA4CA5A
SCHEMBL5363394 0.85 TSHR (0.52) CA12CA1CA2CA4CA5A
SCHEMBL3628330 0.78 TSHR (0.44) TSHRHSD17B10NPSR1MMP9MEN1
SCHEMBL11128694 0.77 CA12 (0.70) CA12CA1CA2CA4CA5A
SCHEMBL11127876 0.74 LPAR3 (0.40) TSHRHSD17B10MMP9MMP1MMP3
SCHEMBL12230161 0.72 TSHR (0.48) TSHRHSD17B10NPSR1MMP9MMP1
SCHEMBL124095 0.71 CA1 (0.54) CA12CA1CA2CA4CA5A
Phosphoric Acid Diethyl Ester Phenyl Ester SCHEMBL133234 0.71 CA1 (0.59) CA12CA1CA2CA4CA5A
SCHEMBL28546756 0.70 CA1 (0.53) CA12CA1CA2CA4CA5A
SCHEMBL10885712 0.70 L3MBTL1 (0.52) CA12CA1CA2CA4CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0013744-B1 CATALYST AND PROCESS FOR THE POLYMERIZATION OF ALPHA-OLEFINS AND A PROCESS FOR PREPARING AN ALPHA-OLEFIN POLYMERIZATION CATALYST COMPONENT Standard Oil Company (US) 1984-11-07 EP disclosed
US-4233182-A High activity catalyst for the polymerization of alpha-olefins STANDARD OIL COMPANY (INDIANA) (US) 1980-11-11 US disclosed
US-4233253-A Method for the preparation of metal salts of phosphorus acid esters STANDARD OIL COMPANY (INDIANA) (US) 1980-11-11 US disclosed
EP-0013744-A1 Catalyst and process for the polymerization of alpha-olefins and a process for preparing an alpha-olefin polymerization catalyst component Standard Oil Company (US) 1980-08-06 EP disclosed