Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | TACR2 | P21452 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SHBG | P04278 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514689 | 1.00 | KCNH2 (0.61) | KCNH2SIGMAR1HTR2AADRA2ASLC6A2 | |
| SCHEMBL4594295 | 1.00 | KCNH2 (0.61) | KCNH2SIGMAR1HTR2AADRA2ASLC6A2 | |
| SCHEMBL9116373 | 1.00 | KCNH2 (0.61) | KCNH2SIGMAR1HTR2AADRA2ASLC6A2 | |
| SCHEMBL9116425 | 1.00 | KCNH2 (0.61) | KCNH2SIGMAR1HTR2AADRA2ASLC6A2 | |
| SCHEMBL9117626 | 0.98 | KCNH2 (0.58) | KCNH2SIGMAR1HTR2AADRA2ASLC6A2 | |
| SCHEMBL28174361 | 0.97 | KCNH2 (0.57) | KCNH2SIGMAR1HTR2AADRA2ASLC6A2 | |
| SCHEMBL29064782 | 0.97 | KCNH2 (0.57) | KCNH2SIGMAR1HTR2AADRA2ASLC6A2 | |
| SCHEMBL9057645 | 0.93 | KCNH2 (0.57) | KCNH2SIGMAR1ADRA2ASLC6A2SLC6A4 | |
| SCHEMBL9116101 | 0.90 | KCNH2 (0.51) | KCNH2SIGMAR1ADRA2ASLC6A2SLC6A4 | |
| SCHEMBL1204768 | 0.88 | NPC1 (0.53) | KCNH2SIGMAR1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405470-A | LUBRICANTS; OXIDATION AND WEAR RESISTANCE | MOBIL OIL CORPORATION (US) | 1983-09-20 | — | — | US | claimed |