SCHEMBL514689

SCHEMBL514689

CCCCCCCCc1ccc(N(CCCCCCCC)c2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 5/20 0.61
SIGMAR1 Q99720 5/20 0.54
HTR2A P28223 2/20 0.50
ADRA2A P08913 3/20 0.49
SLC6A2 P23975 3/20 0.49
SLC6A4 P31645 3/20 0.49
SLC6A3 Q01959 3/20 0.49
ESR1 P03372 2/20 0.49
ADORA3 P0DMS8 2/20 0.49
TACR2 P21452 2/20 0.49
CHRM2 P08172 2/20 0.49
CHRM1 P11229 2/20 0.49
KDM4E B2RXH2 1/20 0.49
ALDH1A1 P00352 1/20 0.49
LMNA P02545 1/20 0.49
SHBG P04278 1/20 0.49
TP53 P04637 1/20 0.49
CYP3A4 P08684 1/20 0.49
HSPD1 P10809 1/20 0.49
ADRB3 P13945 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11129490 1.00 KCNH2 (0.61) KCNH2SIGMAR1HTR2AADRA2ASLC6A2
SCHEMBL4594295 1.00 KCNH2 (0.61) KCNH2SIGMAR1HTR2AADRA2ASLC6A2
SCHEMBL9116373 1.00 KCNH2 (0.61) KCNH2SIGMAR1HTR2AADRA2ASLC6A2
SCHEMBL9116425 1.00 KCNH2 (0.61) KCNH2SIGMAR1HTR2AADRA2ASLC6A2
SCHEMBL9117626 0.98 KCNH2 (0.58) KCNH2SIGMAR1HTR2AADRA2ASLC6A2
SCHEMBL28174361 0.97 KCNH2 (0.57) KCNH2SIGMAR1HTR2AADRA2ASLC6A2
SCHEMBL29064782 0.97 KCNH2 (0.57) KCNH2SIGMAR1HTR2AADRA2ASLC6A2
SCHEMBL9057645 0.93 KCNH2 (0.57) KCNH2SIGMAR1ADRA2ASLC6A2SLC6A4
SCHEMBL9116101 0.90 KCNH2 (0.51) KCNH2SIGMAR1ADRA2ASLC6A2SLC6A4
SCHEMBL1204768 0.88 NPC1 (0.53) KCNH2SIGMAR1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4310163-A1 GREASE COMPOSITION COMPRISING AN IONIC LIQUID Klüber Lubrication München SE & Co. KG (DE) 2024-01-24 EP claimed
CN-107922878-B Fluid with polyalkylene glycol and unsaturated ester 陶氏环球技术有限责任公司 2021-05-25 CN claimed
CN-111040853-A Environment-friendly rare earth ion coated shock absorber oil composition and preparation method thereof 欧陆宝(天津)新材料科技有限公司 2020-04-21 CN claimed
CN-110903884-A Long-acting low-residue high-temperature chain oil 上海派诺化工科技有限公司 2020-03-24 CN claimed
CN-106279852-A Rubber Composition For Flexible Coupling 现代自动车株式会社 2017-01-04 CN claimed
CN-105189717-A Lubricating compositions and methods of use thereof VORA INC 2015-12-23 CN claimed
JP-9272887-A None JP disclosed
CN-118355098-A Viscosity index improver for lubricants based on acrylamide polyisobutylene comb copolymers 巴斯夫欧洲公司 2024-07-16 CN disclosed
CN-115698236-B Engine oil lubricant composition with excellent engine wear protection and corrosion protection and method of preparing the same 埃克森美孚技术与工程公司 2024-07-09 CN disclosed
US-20240196898-A1 INSANITARY INSECT PEST CONTROL METHOD USING CONDENSED HETEROCYCLIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-06-20 US disclosed
CN-118202023-A Polypropylene viscosity modifier and lubricating oil thereof 埃克森美孚化学专利公司 2024-06-14 CN disclosed
EP-3688126-B1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE SHELL INT RESEARCH (NL) 2024-06-12 EP disclosed
CN-118140072-A Toothed belt and method for manufacturing same 三之星机带株式会社 2024-06-04 CN disclosed
CN-1114682-C Poly (neopentyl polyol) ester based coolants and improved additive package HATCO CORP (US) 2003-07-16 CN disclosed
US-6444626-B1 SYNTHETIC COOLANT/LUBRICANT COMPOSITION COMPRISING MIXTURE OF POLY(NEOPENTYL POLYOL) ESTER AND POLYOL ESTER HATCO CORPORATION 2002-09-03 US disclosed
EP-1019463-A1 POLY(NEOPENTYL POLYOL) ESTER BASED COOLANTS AND IMPROVED ADDITIVE PACKAGE HATCO CORPORATION (US) 2000-07-19 EP disclosed
US-5895778-A PRODUCT OF PENTAERYTHRITOL AND LINEAR MONOCARBOXYLIC ACID; ESTERIFICATION, CATALYSIS; MIXTURE WITH POLYOL ESTER, ANTIOXIDANT, YELLOW METAL PACIFIER, AND RUST INHIBITORS; ROTARY SCREW COMPRESSORS HATCO CORPORATION (US) 1999-04-20 US disclosed
WO-1999010455-A1 POLY(NEOPENTYL POLYOL) ESTER BASED COOLANTS AND IMPROVED ADDITIVE PACKAGE HATCO CORPORATION (US) 1999-03-04 WO disclosed
JP-H09272887-A WORKING OIL FOR HYDRAULIC ELEVATOR HITACHI BUILDING SYST CO LTD 1997-10-21 JP disclosed
WO-1995027022-A1 LUBRICATION OIL COMPOSITION EXXON RESEARCH & ENGINEERING COMPANY (US) 1995-10-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240196898-A1 INSANITARY INSECT PEST CONTROL METHOD USING CONDENSED HETEROCYCLIC COMPOUND C1S, C1R, CTRC KCNH2 28/4885SIGMAR1 2645/4885HTR2A 1997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.