Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144844 | 0.91 | TSHR (0.57) | TSHRTHRBALDH1A1USP2POLB | |
| Ethylene Glycol SCHEMBL11168150 | 0.89 | TSHR (0.55) | TSHRTHRBALDH1A1USP2 | |
| SCHEMBL20616531 | 0.88 | TSHR (0.44) | TSHRTHRBALDH1A1 | |
| SCHEMBL17448864 | 0.88 | THRB (0.59) | TSHRTHRBALDH1A1USP2POLB | |
| SCHEMBL56496 | 0.88 | TSHR (0.53) | TSHRTHRBALDH1A1USP2POLB | |
| SCHEMBL996289 | 0.88 | TSHR (0.53) | TSHRTHRBALDH1A1USP2POLB | |
| SCHEMBL11659781 | 0.88 | TSHR (0.53) | TSHRTHRBALDH1A1USP2HTT | |
| SCHEMBL347487 | 0.87 | TSHR (0.61) | TSHRTHRBALDH1A1USP2POLB | |
| SCHEMBL5535254 | 0.87 | TSHR (0.61) | TSHRTHRBALDH1A1USP2POLB | |
| 1,4-Butanediol SCHEMBL1201330 | 0.86 | TSHR (0.52) | TSHRTHRBALDH1A1USP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2011643-B1 | Planographic printing plate precursor and printing method using the same | FUJIFILM CORP (JP) | 2010-10-13 | — | — | EP | disclosed |
| CN-100475881-C | Process for manufacturing polymers | ROHM & HAAS (US) | 2009-04-08 | — | — | CN | disclosed |
| CN-1667025-A | Polymer carriers and process | ROHM & HAAS (US) | 2005-09-14 | — | — | CN | disclosed |
| CN-1590436-A | Process for manufacturing polymers | ROHM & HAAS (US) | 2005-03-09 | — | — | CN | disclosed |
| CN-1590435-A | Process for manufacturing polymers | ROHM & HAAS (US) | 2005-03-09 | — | — | CN | disclosed |
| EP-0075004-A1 | SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES | McCARRY, John D. (US) | 1983-03-30 | — | — | EP | disclosed |
| WO-1982003397-A1 | SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES | MCCARRY JOHN D (US) | 1982-10-14 | — | — | WO | disclosed |