Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 5/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11133238 | 1.00 | KDR (0.43) | KDRMAPK8MAPK9ALDH1A1LMNA | |
| SCHEMBL10604384 | 1.00 | KDR (0.43) | KDRMAPK8MAPK9ALDH1A1LMNA | |
| SCHEMBL10604380 | 1.00 | KDR (0.43) | KDRMAPK8MAPK9ALDH1A1LMNA | |
| SCHEMBL10604386 | 1.00 | KDR (0.43) | KDRMAPK8MAPK9ALDH1A1LMNA | |
| SCHEMBL11616761 | 0.77 | KDR (0.53) | KDRMAPK8MAPK9ALDH1A1LMNA | |
| SCHEMBL5582364 | 0.76 | ALDH1A1 (0.50) | KDRMAPK8MAPK9ALDH1A1LMNA | |
| SCHEMBL5582365 | 0.76 | ALDH1A1 (0.50) | KDRMAPK8MAPK9ALDH1A1LMNA | |
| SCHEMBL9869006 | 0.76 | ALDH1A1 (0.42) | KDRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL15827073 | 0.74 | KDR (0.54) | KDRMAPK8MAPK9ALDH1A1LMNA | |
| SCHEMBL11799571 | 0.73 | CHRNA7 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4394070-A | Helichromic compounds and displays | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-07-19 | — | — | US | disclosed |