Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230959 | 0.82 | NPSR1 (0.65) | KMT2ARAB9ANPC1HPGDSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL11680028 | 0.81 | NPSR1 (0.64) | KMT2ARAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL11219278 | 0.81 | KMT2A (0.51) | KMT2ARAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL11230602 | 0.80 | NPC1 (0.44) | KMT2ARAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL11413240 | 0.79 | NPSR1 (0.57) | KMT2ARAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL11227353 | 0.79 | DHODH (0.50) | KMT2ARAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL11241747 | 0.78 | KMT2A (0.48) | KMT2ARAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL11236589 | 0.77 | KMT2A (0.48) | KMT2ARAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL11243595 | 0.77 | NPC1 (0.53) | KMT2ARAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL11222537 | 0.76 | NPC1 (0.48) | KMT2ARAB9ANPC1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58210056-A | — | — | None | — | — | JP | disclosed |
| JP-S58210056-A | 2-CYANO-1-CYCLOHEXENE DERIVATIVE AND ITS PREPARATION | TAKEDA CHEM IND LTD | 1983-12-07 | — | — | JP | disclosed |