Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 8/20 | 0.46 |
| ▸ | PPARA | Q07869 | 8/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444498 | 0.97 | CTSK (0.49) | CTSKCTSSPPARGPPARACYP1A2 | |
| SCHEMBL10692756 | 0.95 | PPARA (0.50) | CTSKCTSSPPARGPPARACYP1A2 | |
| SCHEMBL13855559 | 0.92 | CTSK (0.47) | CTSKCTSSPPARGPPARACYP1A2 | |
| SCHEMBL432222 | 0.86 | PPARA (0.57) | CTSKCTSSPPARGPPARACYP1A2 | |
| SCHEMBL2541324 | 0.86 | PPARA (0.57) | CTSKCTSSPPARGPPARACYP1A2 | |
| SCHEMBL5351802 | 0.86 | PPARA (0.57) | CTSKCTSSPPARGPPARACYP1A2 | |
| SCHEMBL316084 | 0.86 | PPARA (0.57) | CTSKCTSSPPARGPPARACYP1A2 | |
| SCHEMBL13489723 | 0.86 | PPARA (0.57) | CTSKCTSSPPARGPPARACYP1A2 | |
| SCHEMBL7430468 | 0.85 | PPARG (0.55) | CTSKCTSSPPARGPPARACYP1A2 | |
| SCHEMBL19710006 | 0.85 | CTSK (0.51) | CTSKCTSSPPARGPPARACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4414149-A | POLYPEPTIDE | ARMOUR PHARMACEUTICAL COMPANY (US) | 1983-11-08 | — | — | US | disclosed |