SCHEMBL11136155

SCHEMBL11136155

O=CCC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)C(NC(=O)COc3ccccc3)C2OC1

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CTDSP1 Q9GZU7 1/20 0.37
POLB P06746 2/20 0.36
CMA1 P23946 5/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11140191 0.89 CMA1 (0.44) CTDSP1POLBCMA1L3MBTL1
SCHEMBL11136153 0.87 CTDSP1 (0.40) CTDSP1POLBL3MBTL1
SCHEMBL11285356 0.84 CTDSP1 (0.52) CTDSP1POLBL3MBTL1LMNA
SCHEMBL11140459 0.83 CMA1 (0.36) CMA1
SCHEMBL11143340 0.83 CMA1 (0.36) CTDSP1CMA1L3MBTL1
SCHEMBL11142921 0.83 CTDSP1 (0.35) CTDSP1POLBL3MBTL1LMNA
SCHEMBL11142919 0.83 CTDSP1 (0.35) CTDSP1POLBL3MBTL1LMNA
SCHEMBL11143310 0.78 CMA1 (0.57) CMA1
SCHEMBL11143313 0.78 CMA1 (0.57) CMA1
SCHEMBL11143307 0.78 CMA1 (0.57) CMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4369315-A ANTIBIOTIC RHONE-POULENC INDUSTRIES (FR) 1983-01-18 US claimed
US-4369315-A ANTIBIOTIC RHONE-POULENC INDUSTRIES (FR) 1983-01-18 US disclosed
US-4369314-A Oxacephalosporins RHONE-POULENC INDUSTRIES (FR) 1983-01-18 US disclosed