SCHEMBL11136153

SCHEMBL11136153

CC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)C(NC(=O)COc3ccccc3)C2OC1

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CTDSP1 Q9GZU7 1/20 0.40
POLB P06746 1/20 0.38
TP53 P04637 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ALDH1A1 P00352 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11144720 0.88 MAPK1 (0.47) CTDSP1POLBL3MBTL1ALDH1A1
SCHEMBL11136155 0.87 CTDSP1 (0.37) CTDSP1POLBL3MBTL1
SCHEMBL11142919 0.85 CTDSP1 (0.35) CTDSP1POLBL3MBTL1ALDH1A1
SCHEMBL11142921 0.85 CTDSP1 (0.35) CTDSP1POLBL3MBTL1ALDH1A1
SCHEMBL9475863 0.82 MAPK1 (0.56) CTDSP1L3MBTL1ALDH1A1
SCHEMBL9475868 0.82 MAPK1 (0.56) CTDSP1L3MBTL1ALDH1A1
SCHEMBL11802853 0.82 MAPK1 (0.56) CTDSP1L3MBTL1ALDH1A1
SCHEMBL10975799 0.82 MAPK1 (0.56) CTDSP1L3MBTL1ALDH1A1
SCHEMBL11001684 0.82 MAPK1 (0.56) CTDSP1L3MBTL1ALDH1A1
SCHEMBL11144310 0.82 ALDH1A1 (0.36) CTDSP1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4369315-A ANTIBIOTIC RHONE-POULENC INDUSTRIES (FR) 1983-01-18 US disclosed
US-4369314-A Oxacephalosporins RHONE-POULENC INDUSTRIES (FR) 1983-01-18 US disclosed