Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CDA | P32320 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4370139 | 1.00 | LMNA (0.54) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL4370136 | 1.00 | LMNA (0.54) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL11136645 | 0.99 | LMNA (0.54) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL11135820 | 0.99 | LMNA (0.54) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL11132744 | 0.99 | LMNA (0.54) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL11136445 | 0.99 | LMNA (0.54) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL11135256 | 0.99 | LMNA (0.54) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL11135243 | 0.99 | LMNA (0.54) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL11132633 | 0.99 | LMNA (0.54) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL11135236 | 0.99 | LMNA (0.54) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044085-B1 | NOVEL NUCLEOSIDE DERIVATIVES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-05-25 | — | — | EP | disclosed |