Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 9/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PPID | Q08752 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11139213 | 0.90 | NLRP3 (0.63) | NLRP3POLBHTTMEN1KMT2A | |
| SCHEMBL13971319 | 0.89 | NLRP3 (0.52) | NLRP3POLBPPIDELANEHTT | |
| SCHEMBL11141775 | 0.88 | MAPK1 (0.52) | NLRP3POLBHTTMEN1KMT2A | |
| SCHEMBL11138791 | 0.85 | NLRP3 (0.46) | NLRP3POLBMEN1KMT2ATDP1 | |
| SCHEMBL11135495 | 0.85 | NLRP3 (0.46) | NLRP3POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL13971318 | 0.85 | NLRP3 (0.49) | NLRP3POLBPPIDELANEHTT | |
| SCHEMBL11147579 | 0.84 | TSHR (0.46) | NLRP3TDP1ALDH1A1TSHR | |
| SCHEMBL10816379 | 0.84 | NLRP3 (0.60) | NLRP3POLBPPIDELANEHTT | |
| SCHEMBL11136968 | 0.83 | TSHR (0.44) | NLRP3HTTMEN1KMT2ATDP1 | |
| SCHEMBL11140013 | 0.83 | TSHR (0.48) | NLRP3POLBALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4402734-A | N-(HALOALKYL)-N-(CARBOXYALKYL)ANILINE DERIVATIVE | SUMITOMO CHEMICAL CO., LTD. (JP) | 1983-09-06 | — | — | US | disclosed |