SCHEMBL11136806

SCHEMBL11136806

O=C1c2ccccc2C(=O)C(O)(O)C1(O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.70
RECQL P46063 4/20 0.70
L3MBTL1 Q9Y468 3/20 0.70
ALOX12 P18054 2/20 0.70
EHMT2 Q96KQ7 2/20 0.70
MAPK1 P28482 2/20 0.70
CA1 P00915 1/20 0.70
CA2 P00918 1/20 0.70
TSHR P16473 1/20 0.70
CASP1 P29466 1/20 0.70
CA7 P43166 1/20 0.70
BACE1 P56817 1/20 0.70
CA9 Q16790 1/20 0.70
HSP90AA1 P07900 2/20 0.56
HSP90AB1 P08238 2/20 0.56
MAPT P10636 6/20 0.50
APAF1 O14727 5/20 0.50
TDP2 O95551 5/20 0.50
BLM P54132 3/20 0.50
NSD2 O96028 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28613240 0.83 ALDH1A1 (0.56) ALDH1A1RECQLL3MBTL1ALOX12EHMT2
SCHEMBL208765 0.82 ALDH1A1 (0.70) ALDH1A1RECQLL3MBTL1ALOX12EHMT2
SCHEMBL17986 0.82 CA1 (1.00) ALDH1A1RECQLL3MBTL1ALOX12EHMT2
SCHEMBL29350272 0.82 CA1 (1.00) ALDH1A1RECQLL3MBTL1ALOX12EHMT2
SCHEMBL3658029 0.82 CA1 (1.00) ALDH1A1RECQLL3MBTL1ALOX12EHMT2
SCHEMBL4921601 0.80 CA1 (0.94) ALDH1A1RECQLL3MBTL1ALOX12EHMT2
SCHEMBL11587106 0.80 ALDH1A1 (0.67) ALDH1A1RECQLL3MBTL1ALOX12EHMT2
Water SCHEMBL592691 0.80 CA1 (0.94) ALDH1A1RECQLL3MBTL1ALOX12EHMT2
Ammonia Solution, Strong SCHEMBL1286269 0.80 CA1 (0.94) ALDH1A1RECQLL3MBTL1ALOX12EHMT2
SCHEMBL12856856 0.80 ALDH1A1 (0.67) ALDH1A1RECQLL3MBTL1ALOX12EHMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220401889-A1 Porous membranes comprising sorbent particles for improved urea capture STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) 2022-12-22 US disclosed
US-20110028719-A1 SCREENING METHODS FOR AMYLOID BETA MODULATORS WARATAH PHARMACEUTICALS INC. (CA) 2011-02-03 US disclosed
US-20110028719-A1 SCREENING METHODS FOR AMYLOID BETA MODULATORS WARATAH PHARMACEUTICALS INC. (CA) 2011-02-03 US disclosed
WO-2007134449-A1 SCREENING METHODS FOR AMYLOID BETA MODULATORS WARATAH PHARMACEUTICALS INC. (CA) 2007-11-29 WO disclosed
US-4419368-A 2,2,3,3-TETRAHYDROXY- SYNTEX (U.S.A.) INC. (US) 1983-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110028719-A1 SCREENING METHODS FOR AMYLOID BETA MODULATORS APP, BACE1, IAPP ALDH1A1 4135/4885RECQL 2037/4885L3MBTL1 2473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.