Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11135638 | 0.98 | MAPT (0.59) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL27367712 | 0.95 | MAPT (0.69) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL11135313 | 0.93 | SMN1; SMN2 (0.60) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL11010845 | 0.93 | MAPT (0.66) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL7825139 | 0.89 | MAPT (0.70) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL11007974 | 0.87 | SMN1; SMN2 (0.67) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL11139381 | 0.87 | MAPT (0.59) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL7045419 | 0.86 | MAPT (0.85) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL11131388 | 0.85 | FFAR1 (0.59) | TBXAS1FFAR1PLA2G10PLA2G2A | |
| SCHEMBL9671779 | 0.85 | MAPT (0.83) | MAPTRXFP1HDAC3MAPK1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044541-B1 | AMINOCARBOXYLIC ACIDS, AMINO ALCOHOLS, OR THE DERIVATIVES THEREOF, PROCESSES FOR PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION, CONTAINING AT LEAST ONE OF THESE COMPOUNDS | TEIJIN LIMITED (JP) | 1983-09-21 | — | — | EP | disclosed |
| US-4402975-A | ANTIULCER AGENTS | TEIJIN LIMITED (JP) | 1983-09-06 | — | — | US | disclosed |
| EP-0044541-A1 | Aminocarboxylic acids, amino alcohols, or the derivatives thereof, processes for production thereof, and pharmaceutical composition, containing at least one of these compounds | TEIJIN LIMITED (JP) | 1982-01-27 | — | — | EP | disclosed |