Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.85 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.85 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.71 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.71 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.71 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.71 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.71 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.71 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.60 |
| ▸ | KDM4A | O75164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13851686 | 0.92 | HDAC1 (0.84) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL7825139 | 0.92 | MAPT (0.70) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL2555645 | 0.92 | MAPT (1.00) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL2552651 | 0.92 | MAPT (1.00) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL503837 | 0.92 | MAPT (1.00) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL1008045 | 0.92 | MAPT (1.00) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| Phenylheptanoic Acid SCHEMBL7655508 | 0.92 | MAPT (1.00) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL2548842 | 0.92 | MAPT (1.00) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL2551105 | 0.92 | MAPT (1.00) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL1007173 | 0.92 | MAPT (1.00) | MAPTRXFP1HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160166508-A1 | Method and Composition for Treating Inflammatory Disorders | MEDA AB (SE) | 2016-06-16 | — | — | US | disclosed |
| WO-2003009871-A2 | INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR FOR DECREASING BODY MASS | GENSET S.A. (FR) | 2003-02-06 | — | — | WO | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160166508-A1 | Method and Composition for Treating Inflammatory Disorders | LIPA, HRH2, HRH1 | MAPT 2546/4885RXFP1 2472/4885HDAC1 1634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.