Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28746677 | 0.77 | MAPT (0.64) | MAPTMAPK1KDM4ENSD2SLC6A4 | |
| SCHEMBL22827088 | 0.75 | MAPT (0.60) | MAPTMAPK1KDM4ENSD2SLC6A4 | |
| SCHEMBL4485448 | 0.75 | MAPT (0.64) | MAPTMAPK1KDM4ENSD2ADORA2A | |
| SCHEMBL10444705 | 0.74 | KDM4E (0.49) | MAPTMAPK1KDM4ENSD2SLC6A4 | |
| SCHEMBL5187613 | 0.74 | MAPT (0.68) | MAPTMAPK1KDM4ENSD2ADORA2A | |
| SCHEMBL26714273 | 0.74 | MAPT (0.45) | MAPTMAPK1KDM4ENSD2ADORA2A | |
| SCHEMBL10938974 | 0.73 | MAPT (0.44) | MAPTMAPK1MAOAL3MBTL1MEN1 | |
| SCHEMBL10873188 | 0.73 | MAPT (0.57) | MAPTMAPK1KDM4ENSD2ADORA2A | |
| SCHEMBL11489084 | 0.73 | MAPT (0.50) | MAPTMAPK1KDM4ENSD2MAOA | |
| SCHEMBL10729138 | 0.73 | MAPT (0.57) | MAPTMAPK1KDM4ENSD2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4394070-A | Helichromic compounds and displays | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-07-19 | — | — | US | disclosed |