SCHEMBL4485448

SCHEMBL4485448

Cc1ccc(Sc2cccc3c2C(=O)c2cccc(Sc4ccc(C)cc4)c2C3=O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.64
KDM4E B2RXH2 1/20 0.64
NSD2 O96028 1/20 0.64
MAPK1 P28482 1/20 0.64
HKDC1 Q2TB90 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
P4HB P07237 1/20 0.49
MCL1 Q07820 2/20 0.41
BCL2 P10415 1/20 0.41
DHFR P00374 1/20 0.41
ADORA2A P29274 2/20 0.41
ICAM1 P05362 1/20 0.40
SELE P16581 1/20 0.40
VCAM1 P19320 1/20 0.40
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14207786 0.95 MAPT (0.73) MAPTKDM4ENSD2MAPK1HKDC1
SCHEMBL5187613 0.95 MAPT (0.68) MAPTKDM4ENSD2MAPK1HKDC1
SCHEMBL11580274 0.92 MAPT (0.55) MAPTKDM4ENSD2MAPK1HKDC1
SCHEMBL13797721 0.91 MAPT (0.54) MAPTKDM4ENSD2MAPK1HKDC1
SCHEMBL10356145 0.89 MAPT (0.56) MAPTKDM4ENSD2MAPK1HKDC1
SCHEMBL4465042 0.83 MAPT (0.89) MAPTKDM4ENSD2MAPK1HKDC1
SCHEMBL10355983 0.83 MEN1 (0.54) MAPTKDM4ENSD2MAPK1HKDC1
SCHEMBL6821902 0.82 MAPT (0.64) MAPTKDM4ENSD2MAPK1TDP1
SCHEMBL6365480 0.82 MAPK1 (0.64) MAPTKDM4ENSD2MAPK1HKDC1
SCHEMBL10973924 0.81 MAPT (0.58) MAPTKDM4ENSD2MAPK1HKDC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10759212-B2 Security element LEONHARD KURZ STIFTUNG & CO. KG (DE) 2020-09-01 US disclosed
US-10759212-B2 Security element LEONHARD KURZ STIFTUNG & CO. KG (DE) 2020-09-01 US disclosed
EP-3227122-B1 SECURITY ELEMENT LEONHARD KURZ STIFTUNG & CO KG (DE) 2020-04-08 EP disclosed
US-20180134065-A1 Security Element LEONHARD KURZ STIFTUNG & CO. KG (DE) 2018-05-17 US disclosed
US-20180134065-A1 Security Element LEONHARD KURZ STIFTUNG & CO. KG (DE) 2018-05-17 US disclosed
US-20180134065-A1 Security Element LEONHARD KURZ STIFTUNG & CO. KG (DE) 2018-05-17 US disclosed
US-7494721-B2 Light-emitting device, condensed polycyclic compound used therein and method for producing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-02-24 US disclosed
US-20060051612-A1 Light-emitting device, condensed polycyclic compound used therein and method for producing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2006-03-09 US disclosed
EP-1589089-A1 LIGHT-EMITTING DEVICE, CONDENSED POLYCYCLIC COMPOUND USED THEREIN AND METHOD FOR PRODUCING SAME Nippon Kayaku Kabushiki Kaisha (JP) 2005-10-26 EP disclosed
EP-0931111-B1 ANTHRAQUINONE POLYSULFONAMIDE COLORANTS EASTMAN CHEM CO (US) 2001-10-24 EP disclosed
US-6140517-A Anthraquinone polysulfonamide colorants EASTMAN CHEMICAL COMPANY (US) 2000-10-31 US disclosed
US-6121351-A A POLYMERIC DYE BLENDS IS NOT LEACHABLE, SUBLIMABLE OR EXTRACTABLE AND DO NOT EXUDE FROM THE THERMOPLASTIC COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2000-09-19 US disclosed
EP-0931111-A1 ANTHRAQUINONE POLYSULFONAMIDE COLORANTS EASTMAN CHEMICAL COMPANY (US) 1999-07-28 EP disclosed
EP-0925322-A1 THERMOPLASTIC COMPOSITIONS CONTAINING ANTHRAQUINONE POLYSULFONAMIDE COLORANTS EASTMAN CHEMICAL COMPANY (US) 1999-06-30 EP disclosed
WO-1998010022-A1 ANTHRAQUINONE POLYSULFONAMIDE COLORANTS EASTMAN CHEMICAL COMPANY (US) 1998-03-12 WO disclosed
WO-1998010010-A1 THERMOPLASTIC COMPOSITIONS CONTAINING ANTHRAQUINONE POLYSULFONAMIDE COLORANTS EASTMAN CHEMICAL COMPANY (US) 1998-03-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060051612-A1 Light-emitting device, condensed polycyclic compound used therein and method for producing same CYBA, SCO2, NQO1 MAPT 2457/4885KDM4E 2661/4885NSD2 941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.