Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11593599 | 0.91 | EPAS1 (0.44) | ATMTDP1HSPB1ALDH1A1MAPT | |
| SCHEMBL11591036 | 0.91 | POLB (0.48) | TDP1HSPB1ALDH1A1MAPTMEN1 | |
| SCHEMBL11587007 | 0.90 | ALDH1A1 (0.43) | ATMTDP1HSPB1ALDH1A1MAPT | |
| SCHEMBL10796809 | 0.89 | ALDH1A1 (0.44) | ATMTDP1HSPB1ALDH1A1MAPT | |
| SCHEMBL11735174 | 0.88 | TDP1 (0.53) | ATMTDP1HSPB1ALDH1A1MAPT | |
| SCHEMBL11590789 | 0.88 | POLB (0.40) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL11595300 | 0.88 | MAPK1 (0.44) | TDP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11593158 | 0.88 | MAPT (0.47) | TDP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11588228 | 0.88 | MAPT (0.46) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL11593164 | 0.86 | MAPT (0.46) | TDP1HSPB1ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4407820-A | INSECTICIDES, MITICIDES | ELI LILLY AND COMPANY (US) | 1983-10-04 | — | — | US | disclosed |
| EP-0060951-A1 | Improvements in or relating to N-alkylated diphenylamine derivatives | ELI LILLY AND COMPANY (US) | 1982-09-29 | — | — | EP | disclosed |
| US-4117167-A | INSECTICIDES, ACARICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-26 | — | — | US | disclosed |
| US-4084004-A | Rodenticidal use of diphenylamines | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |