Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UPP1 | Q16831 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5182348 | 0.84 | UPP1 (0.64) | UPP1ALDH1A1CYP2C19CYP2C9TDP1 | |
| SCHEMBL8941878 | 0.82 | UPP1 (0.61) | UPP1ALDH1A1CYP2C19CYP2C9TDP1 | |
| SCHEMBL6655303 | 0.81 | UPP1 (0.68) | UPP1ALDH1A1CYP2C19CYP2C9POLB | |
| SCHEMBL11131319 | 0.80 | UPP1 (0.52) | UPP1ALDH1A1CYP2C19CYP2C9POLB | |
| SCHEMBL10780143 | 0.75 | UPP1 (0.53) | UPP1ALDH1A1CYP2C19CYP2C9KDM4E | |
| SCHEMBL9114390 | 0.74 | UPP1 (0.80) | UPP1ALDH1A1CYP2C19CYP2C9POLB | |
| SCHEMBL16561956 | 0.73 | UPP1 (0.74) | UPP1ALDH1A1CYP2C19CYP2C9POLB | |
| SCHEMBL16561918 | 0.73 | UPP1 (1.00) | UPP1ALDH1A1CYP2C19CYP2C9POLB | |
| SCHEMBL8025123 | 0.73 | UPP1 (0.64) | UPP1ALDH1A1CYP2C19CYP2C9POLB | |
| SCHEMBL16561913 | 0.70 | UPP1 (1.00) | UPP1ALDH1A1CYP2C19CYP2C9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109527-A1 | Water-insoluble monoazo dyestuffs, methods for their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1984-05-30 | — | — | EP | disclosed |